Version 5.4
Homo sapiens Gene: RIC8A
Summary
InnateDB Gene IDBG-15573.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RIC8A
Gene Name resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000177963
Encoded Proteins
IDBP-15577
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
IDBP-603864
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
IDBP-588654
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
IDBP-587305
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
IDBP-593595
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
IDBP-597691
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
IDBP-590948
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
IDBP-597733
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
IDBP-585602
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
IDBP-587045
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:207511-215113
Strand Forward strand
Band p15.5
Transcripts
ENST00000325207 ENSP00000325941
ENST00000526104 ENSP00000432008
ENST00000528357 ENSP00000436610
ENST00000526982 ENSP00000435167
ENST00000532373
ENST00000530889 ENSP00000433968
ENST00000527696 ENSP00000434833
ENST00000527468 ENSP00000433009
ENST00000527728 ENSP00000436192
ENST00000527039
ENST00000530149
ENST00000532241
ENST00000524854 ENSP00000434896
ENST00000529275 ENSP00000431163
ENST00000526557
ENST00000531541
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 28 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001944 vasculature development
GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007369 gastrulation
GO:0008542 visual learning
GO:0009416 response to light stimulus
GO:0042074 cell migration involved in gastrulation
GO:0043547 positive regulation of GTPase activity
GO:0070586 cell-cell adhesion involved in gastrulation
GO:0071711 basement membrane organization
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025485
View Gene Order
ENSBTAG00000002042
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.592292
RefSeq NM_001286134 NM_021932 XM_005253052 XM_006718270
HUGO
OMIM
CCDS CCDS65982 CCDS7690
HPRD 12373
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca