Version 5.4
Bos taurus Gene: ARPP19
Summary
InnateDB Gene IDBG-646646.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARPP19
Gene Name cAMP-regulated phosphoprotein 19
Synonyms ARPP-16; ARPP-19
Species Bos taurus
Ensembl Gene ENSBTAG00000011022
Encoded Proteins
IDBP-699468
cAMP-regulated phosphoprotein 19
IDBP-699469
cAMP-regulated phosphoprotein 19
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000128989:
The 19-kD cAMP-regulated phosphoprotein plays a role in regulating mitosis by inhibiting protein phosphatase-2A (PP2A; see MIM 176915) (summary by Gharbi-Ayachi et al., 2010 [PubMed 21164014]).[supplied by OMIM, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:57923246-57938671
Strand Forward strand
Band
Transcripts
ENSBTAT00000022929 ENSBTAP00000022929
ENSBTAT00000014642 ENSBTAP00000014642
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004864 protein phosphatase inhibitor activity
GO:0005102 receptor binding
GO:0008601 protein phosphatase type 2A regulator activity
GO:0015459 potassium channel regulator activity
GO:0019212 phosphatase inhibitor activity
GO:0051721 protein phosphatase 2A binding
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0007049 cell cycle
GO:0007067 mitotic nuclear division
GO:0043086 negative regulation of catalytic activity
GO:0045722 positive regulation of gluconeogenesis
GO:0050790 regulation of catalytic activity
GO:0051301 cell division
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000128989
View Gene Order
ENSMUSG00000007656
View Gene Order
Pathways
NETPATH
REACTOME
REACT_203310
MASTL Facilitates Mitotic Progression pathway
REACT_216366
M Phase pathway
REACT_215505
Cell Cycle, Mitotic pathway
REACT_214934
Cell Cycle pathway
REACT_211448
Mitotic Prophase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150182
MASTL Facilitates Mitotic Progression pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_765
Mitotic Prophase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_188804
Cell Cycle pathway
REACT_241408
M Phase pathway
REACT_196577
MASTL Facilitates Mitotic Progression pathway
REACT_250557
Mitotic Prophase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q28055
TrEMBL
UniProt Splice Variant
Entrez Gene 282658
UniGene Bt.4823 Bt.68471
RefSeq NM_001113255 NM_174705 XM_005211788
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL M33617 M33618
GenPept AAA30385 AAA30386
RNA Seq Atlas 282658

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca