Version 5.4
Bos taurus Gene: RTF1
Summary
InnateDB Gene IDBG-646293.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RTF1
Gene Name RNA polymerase-associated protein RTF1 homolog
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001671
Encoded Proteins
IDBP-699083
Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137815:
This locus may represent a gene involved in regulation of transcription elongation and chromatin remodeling, based on studies of similar proteins in other organisms. The encoded protein may bind single-stranded DNA. [provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:36980593-37025485
Strand Forward strand
Band
Transcripts
ENSBTAT00000002191 ENSBTAP00000002191
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001711 endodermal cell fate commitment
GO:0006352 DNA-templated transcription, initiation
GO:0016570 histone modification
GO:0019827 stem cell maintenance
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0051571 positive regulation of histone H3-K4 methylation
GO:0080182 histone H3-K4 trimethylation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0016593 Cdc73/Paf1 complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000137815
View Gene Order
ENSMUSG00000027304
View Gene Order
Cross-References
SwissProt
TrEMBL F1N6E9
UniProt Splice Variant
Entrez Gene 518260
UniGene Bt.10050
RefSeq NM_001192485
HUGO HGNC:28996
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02028563
GenPept
RNA Seq Atlas 518260

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca