InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: EEF2

Summary

InnateDB Gene

IDBG-644322.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EEF2

Gene Name

Elongation factor 2

Synonyms

EF-2

Species

Bos taurus

Ensembl Gene

ENSBTAG00000004258

Encoded Proteins

IDBP-696958

Elongation factor 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167658:
This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:21252438-21261327

Strand

Forward strand

Band

Transcripts

ENSBTAT00000005581

ENSBTAP00000005581

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 84 interaction(s) predicted by orthology.

Predicted by orthology
Total	84 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003746	translation elongation factor activity
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0008494	translation activator activity
GO:0019901	protein kinase binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0002244	hematopoietic progenitor cell differentiation
GO:0006412	translation
GO:0006414	translational elongation
GO:0010628	positive regulation of gene expression
GO:0045727	positive regulation of translation