Bos taurus Gene: CHAF1B
Summary
InnateDB Gene IDBG-640512.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHAF1B
Gene Name chromatin assembly factor 1 subunit B
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011880
Encoded Proteins
chromatin assembly factor 1 subunit B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159259:
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:150360988-150386586
Strand Forward strand
Band
Transcripts
ENSBTAT00000015764 ENSBTAP00000015764
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006335 DNA replication-dependent nucleosome assembly
GO:0031497 chromatin assembly
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0033186 CAF-1 complex
GO:0043234 protein complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A5D9H4
UniProt Splice Variant
Entrez Gene 511654
UniGene Bt.24966
RefSeq NM_001098014
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT030593 DAAA02003568
GenPept ABQ13033
RNA Seq Atlas 511654