Version 5.4
Bos taurus Gene: SLCO1C1
Summary
InnateDB Gene IDBG-639024.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLCO1C1
Gene Name solute carrier organic anion transporter family member 1C1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019602
Encoded Proteins
IDBP-691140
solute carrier organic anion transporter family, member 1C1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139155:
This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:89440029-89509795
Strand Reverse strand
Band
Transcripts
ENSBTAT00000026117 ENSBTAP00000026117
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000139155
View Gene Order
ENSMUSG00000030235
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_23988
Transport of organic anions pathway
REACT_22285
Transport of vitamins, nucleosides, and related molecules pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_232951
Transport of vitamins, nucleosides, and related molecules pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_210189
Transport of organic anions pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BC23
UniProt Splice Variant
Entrez Gene 518047
UniGene Bt.38844
RefSeq NM_001191509 XM_005206939
HUGO HGNC:13819
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02014133
GenPept
RNA Seq Atlas 518047

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca