Version 5.4
Bos taurus Gene: TP53BP1
Summary
InnateDB Gene IDBG-633110.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TP53BP1
Gene Name tumor suppressor p53-binding protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021304
Encoded Proteins
IDBP-684861
tumor protein p53 binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000067369:
Gene Information
Type Protein coding
Genomic Location Chromosome 21:55682755-55749862
Strand Reverse strand
Band
Transcripts
ENSBTAT00000028388 ENSBTAP00000028388
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 115 interaction(s) predicted by orthology.
Predicted by orthology
Total 115 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0001104 RNA polymerase II transcription cofactor activity
GO:0002039 p53 binding
GO:0003684 damaged DNA binding
GO:0005515 protein binding
GO:0035064 methylated histone binding
GO:0042162 telomeric DNA binding
Biological Process
GO:0006281 DNA repair
GO:0006366 transcription from RNA polymerase II promoter
GO:0006974 cellular response to DNA damage stimulus
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0000776 kinetochore
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0005657 replication fork
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000067369
View Gene Order
ENSMUSG00000043909
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_97
Recruitment of repair and signaling proteins to double-strand breaks pathway
REACT_1874
Homologous Recombination Repair pathway
REACT_2054
Double-Strand Break Repair pathway
REACT_1587
Homologous recombination repair of replication-independent double-strand breaks pathway
REACT_216
DNA Repair pathway
KEGG
INOH
PID NCI
atm_pathway
ATM pathway
Cross-References
SwissProt
TrEMBL E1BDS6
UniProt Splice Variant
Entrez Gene 509111
UniGene Bt.91168
RefSeq NM_001206397 XM_005222175
HUGO HGNC:11999
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02052963
GenPept
RNA Seq Atlas 509111

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca