InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Slc34a2

Summary

InnateDB Gene

IDBG-164374.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc34a2

Gene Name

solute carrier family 34 (sodium phosphate), member 2

Synonyms

AA536683; D5Ertd227e; NaPi-2b; Npt2b

Species

Mus musculus

Ensembl Gene

ENSMUSG00000029188

Encoded Proteins

IDBP-164378

solute carrier family 34 (sodium phosphate), member 2

IDBP-628031

solute carrier family 34 (sodium phosphate), member 2

IDBP-628032

solute carrier family 34 (sodium phosphate), member 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157765:
The protein encoded by this gene is a pH-sensitive sodium-dependent phosphate transporter. Phosphate uptake is increased at lower pH. Defects in this gene are a cause of pulmonary alveolar microlithiasis. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, May 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:53038082-53071664

Strand

Forward strand

Band

Transcripts

ENSMUST00000094787	ENSMUSP00000092380
ENSMUST00000147243
ENSMUST00000170523	ENSMUSP00000130692
ENSMUST00000168667	ENSMUSP00000132328

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005436	sodium:phosphate symporter activity
GO:0015321	sodium-dependent phosphate transmembrane transporter activity
GO:0019904	protein domain specific binding
GO:0031402	sodium ion binding
GO:0042301	phosphate ion binding

Biological Process

GO:0001701	in utero embryonic development
GO:0006817	phosphate ion transport
GO:0007568	aging
GO:0009750	response to fructose
GO:0030643	cellular phosphate ion homeostasis
GO:0032355	response to estradiol
GO:0035435	phosphate ion transmembrane transport
GO:0035725	sodium ion transmembrane transport
GO:0043627	response to estrogen
GO:0044341	sodium-dependent phosphate transport

Cellular Component

GO:0005903	brush border
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0031526	brush border membrane
GO:0031528	microvillus membrane