InnateDB: Systems Biology of the Innate Immune Response

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Viewing interactions 1 to 20 of 25 hits matching query ( Pathway name: 'Interleukin-2 (IL-2) Signaling Pathway (Human)' )

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Group ID	Interaction	Interactors	Interactor Types	Species	Interaction Level (?)	Interaction Type	Source Database ID(s)	Supporting Publications
272	IL2RA interacts with IL2RA	IL2RA :: IL2RA	protein	Homo sapiens	direct interaction	unspecified	BIOGRID-288290	1	Interaction Details
6594	STAT5A physically interacts with the Il2RA gene promoter	STAT5A :: IL2RA	protein-DNA	Homo sapiens	direct interaction	physical association	IDB-156197	1	Interaction Details
6597	STAT5A interacts with STAT5A	STAT5A :: STAT5A	protein	Homo sapiens	direct interaction	unspecified	BIND-183374	1	Interaction Details
7205	JAK3 phosphorylates IL2RG	IL2RG :: JAK3	protein	Homo sapiens	direct interaction	phosphorylation	IDB-116527	1	Interaction Details
10358	IL2RB interacts with STAT5A	IL2RB :: STAT5A	protein	Homo sapiens	direct interaction	unspecified	BIOGRID-275216	1	Interaction Details
10359	IL2RB and IL2RG	IL2RB :: IL2RG	protein	Homo sapiens	direct interaction	direct interaction	DIP-757E	2	Interaction Details
10361	IL2RB interacts with IL2RG	IL2RB :: IL2RG	protein	Homo sapiens	direct interaction	physical association	IDB-187063 IDB-187062 IDB-187249 IDB-157507	3	Interaction Details
10362	IL2RA interacts with IL2RB	IL2RA :: IL2RB	protein	Homo sapiens	direct interaction	physical association	IDB-157508 IDB-157535 DIP-758E	3	Interaction Details
33380	IL2RB interacts with JAK1	IL2RB :: JAK1	protein	Homo sapiens	direct interaction	unspecified	BIOGRID-318121 IDB-116337 IDB-116143 IDB-116134 BIOGRID-282724 BIOGRID-303382 BIND-183013 BIOGRID-318119 BIOGRID-278360	8	Interaction Details
33384	JAK1 interacts with STAT5A	JAK1 :: STAT5A	protein	Homo sapiens	direct interaction	unspecified	BIOGRID-280121 BIOGRID-280113 BIOGRID-280119 BIOGRID-280117	1	Interaction Details
33404	IL2RB interacts with JAK1	IL2RB :: JAK1	protein	Homo sapiens	direct interaction	physical association	IDB-187074 DIP-1059E	2	Interaction Details
33407	JAK1 interacts with JAK1	JAK1 :: JAK1	protein	Homo sapiens	direct interaction	phosphorylation	IDB-185025 IDB-185105	2	Interaction Details
34089	IL2RG interacts with JAK3	IL2RG :: JAK3	protein	Homo sapiens	direct interaction	unspecified	BIOGRID-282725 IDB-116434 BIOGRID-278361	3	Interaction Details
34090	IL3RB physically interacts with JAK3	IL2RB :: JAK3	protein	Homo sapiens	direct interaction	physical interaction	IDB-116435	1	Interaction Details
34092	JAK3 interacts with STAT5A	JAK3 :: STAT5A	protein	Homo sapiens	direct interaction	unspecified	BIOGRID-18916	1	Interaction Details
34096	JAK1 physically interacts with JAK3	JAK1 :: JAK3	protein	Homo sapiens	direct interaction	physical interaction	IDB-116436 IDB-116437	1	Interaction Details
34106	unknown	IL2RG :: JAK3	protein	Homo sapiens	direct interaction	physical association	DIP-1060E	1	Interaction Details
34107	JAK3 interacts with JAK3	JAK3 :: JAK3	protein	Homo sapiens	direct interaction	phosphorylation	IDB-116526 IDB-116448 IDB-116525	2	Interaction Details
34108	JAK3 interacts with JAK3	JAK3 :: JAK3	protein	Homo sapiens	direct interaction	unspecified	BIND-262116 BIND-262118	1	Interaction Details
47727	JAK3 interacts with STAT5B	JAK3 :: STAT5B	protein	Homo sapiens	direct interaction	unspecified	BIOGRID-280116	1	Interaction Details

InnateDB is being developed jointly by the Brinkman Laboratory, Simon Fraser University and the Hancock Laboratory, University of British Columbia, Vancouver, British Columbia, Canada and the Lynn Laboratory, Teagasc Animal Bioscience Department, Ireland.
Funding is provided by Genome Canada through the Pathogenomics of Innate Immunity (PI2) project, and the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative.
InnateDB curated interactions are licensed under the Design Science License, all other data is licensed under the terms of the originating database.