InnateDB Protein
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IDBP-9600.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NUPL2
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Protein Name
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nucleoporin like 2
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Synonyms
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CG1; hCG1; NLP_1; NLP-1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000258742
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InnateDB Gene
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IDBG-9598 (NUPL2)
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Protein Structure
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Function |
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope. {ECO:0000269PubMed:10610322, ECO:0000269PubMed:16000379}.
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Subcellular Localization |
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Excluded from the nucleolus.
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Disease Associations |
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Tissue Specificity |
Ubiquitously expressed. {ECO:0000269PubMed:10358091}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
10
[view]
|
Protein-Protein |
10
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000571
Zinc finger, CCCH-type
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PFAM |
PF00642
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PRINTS |
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PIRSF |
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SMART |
SM00356
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TIGRFAMs |
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Modification |
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SwissProt |
O15504
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PhosphoSite |
PhosphoSite-O15504
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
11097
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UniGene |
Hs.606715
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RefSeq |
NP_031368
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HUGO |
HGNC:17010
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OMIM |
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CCDS |
CCDS5379
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HPRD |
14855
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IMGT |
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EMBL |
AK298183
BC005327
BC039333
BT007409
CH236948
U97198
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GenPept |
AAC33794
AAH05327
AAH39333
AAP36077
BAG60454
EAL24260
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