InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC6A6

Summary

InnateDB Protein

IDBP-813501.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC6A6

Protein Name

solute carrier family 6 (neurotransmitter transporter), member 6

Synonyms

TAUT;

Species

Homo sapiens

Ensembl Protein

ENSP00000480890

InnateDB Gene

IDBG-20066 (SLC6A6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005328	neurotransmitter:sodium symporter activity
GO:0005368	taurine transmembrane transporter activity
GO:0005369	taurine:sodium symporter activity
GO:0030977	taurine binding

Biological Process

GO:0006520	cellular amino acid metabolic process
GO:0006810	transport
GO:0006811	ion transport
GO:0006836	neurotransmitter transport
GO:0006865	amino acid transport
GO:0015734	taurine transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000175 Sodium:neurotransmitter symporter
IPR002434 Sodium:neurotransmitter symporter, taurine

PFAM

PF00209

PRINTS

PR00176
PR01200

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-P31641

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AC090941 AC090952 AC093496 AF346763 BC006252 BC111489 BC137128 BC137129 CH471055 U09220 U16120 Z18956

GenPept

AAA50842 AAC50443 AAH06252 AAI11490 AAI37129 AAI37130 AAK30132 CAA79481 EAW64192 EAW64193 EAW64194

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca