Version 5.4
Homo sapiens Protein: SLC6A6
Summary
InnateDB Protein IDBP-813495.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC6A6
Protein Name solute carrier family 6 (neurotransmitter transporter), member 6
Synonyms TAUT;
Species Homo sapiens
Ensembl Protein ENSP00000481625
InnateDB Gene IDBG-20066 (SLC6A6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005328 neurotransmitter:sodium symporter activity
Biological Process
GO:0006520 cellular amino acid metabolic process
GO:0006810 transport
GO:0006811 ion transport
GO:0006836 neurotransmitter transport
GO:0006865 amino acid transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000175 Sodium:neurotransmitter symporter
IPR002434 Sodium:neurotransmitter symporter, taurine
PFAM PF00209
PRINTS PR00176
PR01200
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P31641
PhosphoSite PhosphoSite-P31641
TrEMBL C9JPV1
UniProt Splice Variant
Entrez Gene 6533
UniGene
RefSeq
HUGO HGNC:11052
OMIM 186854
CCDS
HPRD
IMGT
EMBL AC090941 AC090952 AC093496 AF346763 BC006252 BC111489 BC137128 BC137129 CH471055 U09220 U16120 Z18956
GenPept AAA50842 AAC50443 AAH06252 AAI11490 AAI37129 AAI37130 AAK30132 CAA79481 EAW64192

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca