Version 5.4
Homo sapiens Protein: POLR3E
Summary
InnateDB Protein IDBP-750824.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLR3E
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000456967
InnateDB Gene IDBG-19931 (POLR3E)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 16 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001056 RNA polymerase III activity
GO:0003899 DNA-directed RNA polymerase activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006383 transcription from RNA polymerase III promoter
GO:0006385 transcription elongation from RNA polymerase III promoter
GO:0006386 termination of RNA polymerase III transcription
GO:0010467 gene expression
GO:0032481 positive regulation of type I interferon production
GO:0045087 innate immune response
GO:0051607 defense response to virus
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005666 DNA-directed RNA polymerase III complex
GO:0005813 centrosome
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR006886 DNA-directed RNA polymerase III subunit Rpc5
PFAM PF04801
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NVU0
PhosphoSite PhosphoSite-Q9NVU0
TrEMBL H3BSI5
UniProt Splice Variant
Entrez Gene 55718
UniGene Hs.596127
RefSeq NP_001244962
HUGO HGNC:30347
OMIM
CCDS CCDS58432
HPRD 15155
IMGT
EMBL AB040885 AC009034 AC092338 AK001371 AK023160 AK023231 AK296813 AK300735 AY092085 BC000285
GenPept AAH00285 AAM18215 BAA91655 BAA95976 BAB14437 BAB14481 BAG59386 BAG62408

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca