InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NDUFAB1

Summary

InnateDB Protein

IDBP-747569.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NDUFAB1

Protein Name

Synonyms

ACP; FASN2A; SDAP;

Species

Homo sapiens

Ensembl Protein

ENSP00000458770

InnateDB Gene

IDBG-20621 (NDUFAB1)

Protein Structure

UniProt Annotation

Function

Carrier of the growing fatty acid chain in fatty acid biosynthesis in mitochondria. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000036	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process
GO:0005504	fatty acid binding
GO:0005509	calcium ion binding
GO:0008137	NADH dehydrogenase (ubiquinone) activity

Biological Process

GO:0006120	mitochondrial electron transport, NADH to ubiquinone
GO:0006633	fatty acid biosynthetic process
GO:0009249	protein lipoylation
GO:0022904	respiratory electron transport chain
GO:0044237	cellular metabolic process
GO:0044281	small molecule metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005747	mitochondrial respiratory chain complex I
GO:0005759	mitochondrial matrix
GO:0031966	mitochondrial membrane