Version 5.4
Homo sapiens Protein: PIK3C3
Summary
InnateDB Protein IDBP-727843.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIK3C3
Protein Name
Synonyms hVps34; VPS34;
Species Homo sapiens
Ensembl Protein ENSP00000473061
InnateDB Gene IDBG-2711 (PIK3C3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 50 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 50 [view]
Protein-Protein 47 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016301 kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0045087 innate immune response (InnateDB)
GO:0046854 phosphatidylinositol phosphorylation
GO:0048015 phosphatidylinositol-mediated signaling
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain
IPR011009 Protein kinase-like domain
PFAM PF00454
PRINTS
PIRSF
SMART SM00146
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL M0R386
UniProt Splice Variant
Entrez Gene 5289
UniGene Hs.656958
RefSeq
HUGO HGNC:8974
OMIM 602609
CCDS
HPRD 04009
IMGT
EMBL AC087683
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca