InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MALT1

Summary

InnateDB Protein

IDBP-697544.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MALT1

Protein Name

mucosa associated lymphoid tissue lymphoma translocation gene 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000043692

InnateDB Gene

IDBG-644866 (MALT1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.

Predicted by orthology
Total	32 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0004197	cysteine-type endopeptidase activity
GO:0004842	ubiquitin-protein transferase activity
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0008233	peptidase activity
GO:0019209	kinase activator activity
GO:0043621	protein self-association

Biological Process

GO:0001923	B-1 B cell differentiation
GO:0002237	response to molecule of bacterial origin
GO:0002726	positive regulation of T cell cytokine production
GO:0006508	proteolysis
GO:0007250	activation of NF-kappaB-inducing kinase activity
GO:0009620	response to fungus
GO:0016567	protein ubiquitination
GO:0032743	positive regulation of interleukin-2 production
GO:0042098	T cell proliferation
GO:0042113	B cell activation
GO:0042981	regulation of apoptotic process
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087	innate immune response
GO:0050852	T cell receptor signaling pathway
GO:0050856	regulation of T cell receptor signaling pathway
GO:0050870	positive regulation of T cell activation
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0051168	nuclear export
GO:0051259	protein oligomerization

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0043234	protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR001309 Peptidase C14, ICE, catalytic subunit p20
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR011029 Death-like domain
IPR011600 Peptidase C14, caspase domain
IPR013098 Immunoglobulin I-set
IPR013151 Immunoglobulin

PFAM

PF00656
PF07679
PF00047

PRINTS

PIRSF

SMART

SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite