InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.20599

Summary

InnateDB Protein

IDBP-696694.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.20599

Protein Name

ubiquitin carboxyl-terminal hydrolase 14

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000025580

InnateDB Gene

IDBG-644085 (BT.20599)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 45 interaction(s) predicted by orthology.

Predicted by orthology
Total	45 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004221	ubiquitin thiolesterase activity
GO:0004843	ubiquitin-specific protease activity
GO:0004866	endopeptidase inhibitor activity
GO:0005515	protein binding
GO:0008233	peptidase activity
GO:0008234	cysteine-type peptidase activity
GO:0016787	hydrolase activity
GO:0036459	ubiquitinyl hydrolase activity
GO:0070628	proteasome binding

Biological Process

GO:0006508	proteolysis
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0007268	synaptic transmission
GO:0010951	negative regulation of endopeptidase activity
GO:0016579	protein deubiquitination
GO:0050920	regulation of chemotaxis
GO:0061136	regulation of proteasomal protein catabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0009986	cell surface
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0045202	synapse

Protein Structure and Domains

PDB ID

InterPro

IPR000626 Ubiquitin-like
IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR028889 Ubiquitin carboxyl-terminal hydrolase-like domain
IPR029071 Ubiquitin-related domain

PFAM

PF00240
PF14560
PF00443

PRINTS

PIRSF

SMART

SM00213

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite