InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DSC2

Summary

InnateDB Protein

IDBP-696351.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DSC2

Protein Name

desmocollin-2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000011306

InnateDB Gene

IDBG-643772 (DSC2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion
GO:0009267	cellular response to starvation
GO:0086005	ventricular cardiac muscle cell action potential
GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion
GO:0086069	bundle of His cell to Purkinje myocyte communication
GO:0086091	regulation of heart rate by cardiac conduction

Cellular Component

GO:0005886	plasma membrane
GO:0005913	cell-cell adherens junction
GO:0014704	intercalated disc
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030057	desmosome
GO:0031410	cytoplasmic vesicle
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000233 Cadherin, cytoplasmic domain
IPR002126 Cadherin
IPR009122 Desmosomal cadherin
IPR009124 Cadherin/Desmocollin
IPR014868 Cadherin prodomain
IPR015919 Cadherin-like

PFAM

PF01049
PF00028
PF08758

PRINTS

PR00205
PR01818
PR01820

PIRSF

SMART

SM00112
SM01055

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt