Version 5.4
Bos taurus Protein: MDH2
Summary
InnateDB Protein IDBP-692350.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MDH2
Protein Name malate dehydrogenase, mitochondrial
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000012454
InnateDB Gene IDBG-640116 (MDH2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016615 malate dehydrogenase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0030060 L-malate dehydrogenase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006099 tricarboxylic acid cycle
GO:0006108 malate metabolic process
GO:0006475 internal protein amino acid acetylation
GO:0044262 cellular carbohydrate metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001236 Lactate/malate dehydrogenase, N-terminal
IPR001557 L-lactate/malate dehydrogenase
IPR010097 Malate dehydrogenase, type 1
PFAM PF00056
PRINTS PR00086
PIRSF PIRSF000102
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q58DR9
UniProt Splice Variant
Entrez Gene 281306
UniGene
RefSeq NP_001013605
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT021528 DAAA02058200
GenPept AAX46375

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca