Version 5.4
Bos taurus Protein: PLBD1
Summary
InnateDB Protein IDBP-691498.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLBD1
Protein Name Phospholipase B-like 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000020677
InnateDB Gene IDBG-639342 (PLBD1)
Protein Structure
UniProt Annotation
Function Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids (By similarity). However, in view of the small size of the putative binding pocket, it has been proposed that it may act rather as an amidase or a peptidase (PubMed:23934913). {ECO:0000250, ECO:0000269PubMed:23934913}.
Subcellular Localization Lysosome {ECO:0000269PubMed:23934913}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0016042 lipid catabolic process
Cellular Component
GO:0005764 lysosome
Protein Structure and Domains
PDB ID
InterPro IPR007000 Phospholipase B-like
PFAM PF04916
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9GL30
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 317710
UniGene Bt.12805
RefSeq NP_001159770
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AJ299408 BC149435 DAAA02014236 DAAA02014237 DAAA02014238 DAAA02014239 DAAA02014240
GenPept AAI49436 CAC13971

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca