InnateDB Protein
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IDBP-686167.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GNPTG
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Protein Name
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N-acetylglucosamine-1-phosphotransferase subunit gamma
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000018766
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InnateDB Gene
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IDBG-634384 (GNPTG)
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Protein Structure
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Function |
Non-catalytic subunit of the N-acetylglucosamine-1- phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. Binds and presents the high mannose glycans of the acceptor to the catalytic alpha and beta subunits (GNPTAB). Enhances the rate of N-acetylglucosamine- 1-phosphate transfer to the oligosaccharides of acid hydrolase acceptors (By similarity). {ECO:0000250}.
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Subcellular Localization |
Secreted {ECO:0000250}. Golgi apparatus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR009011
Mannose-6-phosphate receptor binding domain
IPR012913
Glucosidase II beta subunit-like
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PFAM |
PF07915
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q58CS8
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PhosphoSite |
PhosphoSite-
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TrEMBL |
M5FJT7
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UniProt Splice Variant |
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Entrez Gene |
508713
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UniGene |
Bt.64893
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RefSeq |
NP_001017428
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC142266
BT021869
GJ062847
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GenPept |
AAI42267
AAX46716
DAA15559
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