Version 5.4
Bos taurus Protein: ADAMTS1
Summary
InnateDB Protein IDBP-681731.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAMTS1
Protein Name A disintegrin and metalloproteinase with thrombospondin motifs 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000000944
InnateDB Gene IDBG-630287 (ADAMTS1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008201 heparin binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0001542 ovulation from ovarian follicle
GO:0001822 kidney development
GO:0006508 proteolysis
GO:0060347 heart trabecula formation
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005604 basement membrane
GO:0005737 cytoplasm
GO:0031012 extracellular matrix
GO:0031410 cytoplasmic vesicle
Protein Structure and Domains
PDB ID
InterPro IPR000884 Thrombospondin, type 1 repeat
IPR001590 Peptidase M12B, ADAM/reprolysin
IPR002870 Peptidase M12B, propeptide
IPR006586 ADAM, cysteine-rich
IPR010294 ADAM-TS Spacer 1
IPR013273 Peptidase M12B, ADAM-TS
IPR013274 Peptidase M12B, ADAM-TS1
IPR013277 Peptidase M12B, ADAM-TS8
PFAM PF00090
PF01421
PF01562
PF08516
PF05986
PRINTS PR01857
PR01858
PR01861
PIRSF
SMART SM00209
SM00608
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A7MB07
UniProt Splice Variant
Entrez Gene 512171
UniGene Bt.12010
RefSeq NP_001094550
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151273 DAAA02000225
GenPept AAI51274

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca