Version 5.4
Bos taurus Protein: MOCS2
Summary
InnateDB Protein IDBP-680810.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MOCS2
Protein Name Molybdopterin synthase catalytic subunit
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000007087
InnateDB Gene IDBG-629410 (MOCS2)
Protein Structure
UniProt Annotation
Function Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. {ECO:0000255HAMAP-Rule:MF_03052}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000255HAMAP- Rule:MF_03052}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016740 transferase activity
GO:0030366 molybdopterin synthase activity
GO:0042802 identical protein binding
Biological Process
GO:0006777 Mo-molybdopterin cofactor biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0019008 molybdopterin synthase complex
Protein Structure and Domains
PDB ID
InterPro IPR003448 Molybdopterin biosynthesis MoaE
PFAM PF02391
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A4FUY7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 507986
UniGene Bt.74353
RefSeq NP_001014867
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123458 BT021515
GenPept AAI23459 AAX46362

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca