Version 5.4
| Homo sapiens Protein: FGFRL1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-6369.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | FGFRL1 | ||||||||
| Protein Name | fibroblast growth factor receptor-like 1 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000264748 | ||||||||
| InnateDB Gene | IDBG-6367 (FGFRL1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Has a negative effect on cell proliferation. {ECO:0000250}. | ||||||||
| Subcellular Localization | Membrane {ECO:0000269PubMed:12813049}; Single-pass type I membrane protein {ECO:0000269PubMed:12813049}. Note=Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen. {ECO:0000269PubMed:11031111, ECO:0000269PubMed:11267671, ECO:0000269PubMed:11418238}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR003598
Immunoglobulin subtype 2 IPR003599 Immunoglobulin subtype IPR007110 Immunoglobulin-like domain IPR013098 Immunoglobulin I-set IPR013106 Immunoglobulin V-set domain IPR013151 Immunoglobulin |
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| PFAM |
PF07679
PF07686 PF00047 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00408
SM00409 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8N441 | ||||||||
| PhosphoSite | PhosphoSite-Q8N441 | ||||||||
| TrEMBL | D6REM7 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 53834 | ||||||||
| UniGene | Hs.628675 | ||||||||
| RefSeq | NP_068742 | ||||||||
| HUGO | HGNC:3693 | ||||||||
| OMIM | 605830 | ||||||||
| CCDS | CCDS3344 | ||||||||
| HPRD | 16163 | ||||||||
| IMGT | |||||||||
| EMBL | AC019103 AF279689 AF312678 AJ277437 AK314365 AY358303 BC015228 BC036769 | ||||||||
| GenPept | AAH15228 AAH36769 AAK15273 AAK26742 AAQ88670 BAG36996 CAC14171 | ||||||||