InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MEFV

Summary

InnateDB Protein

IDBP-602444.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MEFV

Protein Name

Mediterranean fever

Synonyms

FMF; MEF; TRIM20;

Species

Homo sapiens

Ensembl Protein

ENSP00000444615

InnateDB Gene

IDBG-11729 (MEFV)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.

Experimentally validated
Total	20 [view]
Protein-Protein	18 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0008270	zinc ion binding

Biological Process

GO:0006954	inflammatory response
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005622

intracellular

Protein Structure and Domains

PDB ID

InterPro

IPR000315 Zinc finger, B-box
IPR004020 DAPIN domain
IPR011029 Death-like domain

PFAM

PF00643
PF02758

PRINTS

PIRSF

SMART

SM00336

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F5H595

UniProt Splice Variant

Entrez Gene

4210

UniGene

Hs.632221

RefSeq

HUGO

HGNC:6998

OMIM

608107

CCDS

HPRD

02012

IMGT

EMBL

AJ003147

GenPept