InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CHD8

Summary

InnateDB Protein

IDBP-601788.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CHD8

Protein Name

chromodomain helicase DNA binding protein 8

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000451442

InnateDB Gene

IDBG-2645 (CHD8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	39 [view]
Protein-Protein	36 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0005524	ATP binding
GO:0016787	hydrolase activity

Biological Process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000330 SNF2-related
IPR001650 Helicase, C-terminal
IPR006935 Helicase/UvrB domain
IPR011545 DEAD/DEAH box helicase domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00176
PF00271
PF04851
PF00270

PRINTS

PIRSF

SMART

SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite