Version 5.4
Homo sapiens Protein: NOVA1
Summary
InnateDB Protein IDBP-595597.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NOVA1
Protein Name neuro-oncological ventral antigen 1
Synonyms Nova-1;
Species Homo sapiens
Ensembl Protein ENSP00000438875
InnateDB Gene IDBG-4123 (NOVA1)
Protein Structure
UniProt Annotation
Function May regulate RNA splicing or metabolism in a specific subset of developing neurons.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity Brain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 122 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 122 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006396 RNA processing
GO:0007268 synaptic transmission
GO:0007626 locomotory behavior
GO:0008380 RNA splicing
GO:0051252 regulation of RNA metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR004087 K Homology domain
IPR004088 K Homology domain, type 1
PFAM PF00013
PF13014
PRINTS
PIRSF
SMART SM00322
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51513
PhosphoSite PhosphoSite-P51513
TrEMBL F8VW64
UniProt Splice Variant
Entrez Gene 4857
UniGene Hs.667349
RefSeq NP_002506
HUGO HGNC:7886
OMIM 602157
CCDS CCDS32061
HPRD 03693
IMGT
EMBL AK289639 AK291022 AK301526 AL079343 AL132716 BC075038 BC075039 CH471078 U04840 Z70771
GenPept AAA16022 AAH75038 AAH75039 BAF82328 BAF83711 BAH13506 CAA94810 EAW65990 EAW65991 EAW65992 EAW65993 EAW65995

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca