Version 5.4
Homo sapiens Protein: TDP1
Summary
InnateDB Protein IDBP-593100.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TDP1
Protein Name tyrosyl-DNA phosphodiesterase 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000450628
InnateDB Gene IDBG-15629 (TDP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008081 phosphoric diester hydrolase activity
Biological Process
GO:0006281 DNA repair
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR010347 Tyrosyl-DNA phosphodiesterase I
PFAM PF06087
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3V5F9
UniProt Splice Variant
Entrez Gene 55775
UniGene Hs.209945
RefSeq
HUGO HGNC:18884
OMIM 607198
CCDS
HPRD 06226
IMGT
EMBL AL137128
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca