InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PAPOLA

Summary

InnateDB Protein

IDBP-592953.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PAPOLA

Protein Name

poly(A) polymerase alpha

Synonyms

PAP;

Species

Homo sapiens

Ensembl Protein

ENSP00000450534

InnateDB Gene

IDBG-19245 (PAPOLA)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.

Experimentally validated
Total	40 [view]
Protein-Protein	39 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0004652	polynucleotide adenylyltransferase activity
GO:0016779	nucleotidyltransferase activity

Biological Process

GO:0031123	RNA 3'-end processing
GO:0043631	RNA polyadenylation

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR007010 Poly(A) polymerase, RNA-binding domain
IPR007012 Poly(A) polymerase, central domain
IPR011068 Nucleotidyltransferase, class I, C-terminal-like

PFAM

PF04926
PF04928

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3V2A0

UniProt Splice Variant

Entrez Gene

10914

UniGene

Hs.731218

RefSeq

HUGO

HGNC:14981

OMIM

605553

CCDS

HPRD

10407

IMGT

EMBL

AL163051

GenPept