Version 5.4
Homo sapiens Protein: RASGRP1
Summary
InnateDB Protein IDBP-591536.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RASGRP1
Protein Name RAS guanyl releasing protein 1 (calcium and DAG-regulated)
Synonyms CALDAG-GEFI; CALDAG-GEFII; hRasGRP1; RASGRP; V;
Species Homo sapiens
Ensembl Protein ENSP00000454053
InnateDB Gene IDBG-5885 (RASGRP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID
InterPro IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
IPR002048 EF-hand domain
IPR023578 Ras guanine nucleotide exchange factor domain
PFAM PF00617
PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00147
SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YNK9
UniProt Splice Variant
Entrez Gene 10125
UniGene Hs.591127
RefSeq
HUGO HGNC:9878
OMIM 603962
CCDS
HPRD 04909
IMGT
EMBL AC116158 AC124306
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca