Version 5.4
Homo sapiens Protein: LRP6
Summary
InnateDB Protein IDBP-590181.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LRP6
Protein Name low density lipoprotein receptor-related protein 6
Synonyms ADCAD2;
Species Homo sapiens
Ensembl Protein ENSP00000445083
InnateDB Gene IDBG-20075 (LRP6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 60 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 60 [view]
Protein-Protein 59 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000033 LDLR class B repeat
IPR000742 Epidermal growth factor-like domain
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
PFAM PF00058
PF00008
PF00057
PRINTS PR00261
PIRSF
SMART SM00135
SM00181
SM00192
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F5H0Z3
UniProt Splice Variant
Entrez Gene 4040
UniGene Hs.658913
RefSeq
HUGO HGNC:6698
OMIM 603507
CCDS
HPRD 04617
IMGT
EMBL AC007537 AC007621 AK074543
GenPept BAG51971

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca