InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LTBR

Summary

InnateDB Protein

IDBP-587856.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LTBR

Protein Name

lymphotoxin beta receptor (TNFR superfamily, member 3)

Synonyms

CD18; D12S370; LT-BETA-R; TNF-R-III; TNFCR; TNFR-RP; TNFR2-RP; TNFR3; TNFRSF3;

Species

Homo sapiens

Ensembl Protein

ENSP00000440875

InnateDB Gene

IDBG-13973 (LTBR)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	29 [view]
Protein-Protein	28 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0031625	ubiquitin protein ligase binding
GO:0042802	identical protein binding

Biological Process

GO:0006915	apoptotic process
GO:0007165	signal transduction
GO:0016032	viral process
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087	innate immune response (InnateDB)
GO:0046330	positive regulation of JNK cascade
GO:0071260	cellular response to mechanical stimulus
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway