InnateDB Protein
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IDBP-474239.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CCL28
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Protein Name
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chemokine (C-C motif) ligand 28
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000426424
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InnateDB Gene
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IDBG-19270 (CCL28)
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Protein Structure
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Function |
Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.
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Subcellular Localization |
Secreted.
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Disease Associations |
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Tissue Specificity |
Preferentially expressed by epithelial cells of diverse tissues including normal and pathological colon, salivary gland, mammary gland, trachea and rectum. Also found in prostate, spleen, thyroid, psoriasis skin and in lower levels in peripheral blood leukocytes, small intestine, Peyer patches, stomach and normal skin.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001811
Chemokine interleukin-8-like domain
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PFAM |
PF00048
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PRINTS |
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PIRSF |
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SMART |
SM00199
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TIGRFAMs |
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Modification |
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SwissProt |
Q9NRJ3
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PhosphoSite |
PhosphoSite-Q9NRJ3
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TrEMBL |
D6RC73
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UniProt Splice Variant |
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Entrez Gene |
56477
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UniGene |
Hs.656904
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RefSeq |
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HUGO |
HGNC:17700
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OMIM |
605240
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CCDS |
CCDS3944
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HPRD |
05577
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IMGT |
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EMBL |
AC025457
AF110384
AF220210
AF266504
AK312120
BC062668
BC069532
CH471119
EF064761
HM067700
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GenPept |
AAF87205
AAG16691
AAG43193
AAH62668
AAH69532
ABK41944
ADH95184
BAG35056
EAW56057
EAW56058
EAW56059
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