Version 5.4
Homo sapiens Protein: DSEL
Summary
InnateDB Protein IDBP-4667.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DSEL
Protein Name dermatan sulfate epimerase-like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000310565
InnateDB Gene IDBG-4665 (DSEL)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in different brain areas as well as in multiple other peripheral tissues. {ECO:0000269PubMed:12556911}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008146 sulfotransferase activity
GO:0016853 isomerase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0030203 glycosaminoglycan metabolic process
GO:0030204 chondroitin sulfate metabolic process
GO:0030208 dermatan sulfate biosynthetic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0000139 Golgi membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000863 Sulfotransferase domain
IPR008929 Chondroitin AC/alginate lyase
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00685
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IZU8
PhosphoSite PhosphoSite-Q8IZU8
TrEMBL
UniProt Splice Variant
Entrez Gene 92126
UniGene Hs.642330
RefSeq NP_115536
HUGO HGNC:18144
OMIM 611125
CCDS CCDS11995
HPRD 10720
IMGT
EMBL AC110597 AF480435 BC062557 BC117325
GenPept AAH62557 AAI17326 AAN32895

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca