Version 5.4
Homo sapiens Protein: PATZ1
Summary
InnateDB Protein IDBP-4574.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PATZ1
Protein Name POZ (BTB) and AT hook containing zinc finger 1
Synonyms dJ400N23; MAZR; PATZ; RIAZ; ZBTB19; ZNF278; ZSG;
Species Homo sapiens
Ensembl Protein ENSP00000337520
InnateDB Gene IDBG-4572 (PATZ1)
Protein Structure
UniProt Annotation
Function Transcriptional repressor. {ECO:0000269PubMed:10713105}.
Subcellular Localization Nucleus {ECO:0000269PubMed:10713105}.
Disease Associations Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1.
Tissue Specificity Ubiquitous.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR007087 Zinc finger, C2H2
IPR011333 BTB/POZ fold
IPR013069 BTB/POZ
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PF00651
PRINTS
PIRSF
SMART SM00225
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9HBE1
PhosphoSite PhosphoSite-Q9HBE1
TrEMBL Q9HD72
UniProt Splice Variant
Entrez Gene 23598
UniGene Hs.731398
RefSeq NP_114439
HUGO HGNC:13071
OMIM 605165
CCDS CCDS13895
HPRD 05522
IMGT
EMBL AC005003 AF119256 AF242522 AF254082 AF254083 AF254084 AF254085 AL096880 AY028384 BC021091 CH471095 CR456613
GenPept AAF01349 AAF32518 AAF99602 AAG09031 AAG09032 AAG09033 AAG09034 AAH21091 AAK19024 CAB51404 CAG30499 EAW59968 EAW59971

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca