Version 5.4
Homo sapiens Protein: STYXL1
Summary
InnateDB Protein IDBP-379682.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STYXL1
Protein Name serine/threonine/tyrosine interacting-like 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000406073
InnateDB Gene IDBG-22888 (STYXL1)
Protein Structure
UniProt Annotation
Function Probable pseudophosphatase. Contains a Ser residue instead of a conserved Cys residue in the dsPTPase catalytic loop which probably renders it catalytically inactive as a phosphatase. The binding pocket may be however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0035556 intracellular signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001763 Rhodanese-like domain
IPR029021 Protein-tyrosine phosphatase-like
PFAM PF00581
PRINTS
PIRSF
SMART SM00450
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y6J8
PhosphoSite PhosphoSite-Q9Y6J8
TrEMBL
UniProt Splice Variant
Entrez Gene 51657
UniGene Hs.11615
RefSeq
HUGO HGNC:18165
OMIM
CCDS
HPRD 13256
IMGT
EMBL AC006330 AF069762 AF169647 AF169648 AF188201 AF188202 AF188203 AF188204 BC024035
GenPept AAD36983 AAD53723 AAD53724 AAF04111 AAF04112 AAF04113 AAF04114 AAH24035 AAS07535

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca