Version 5.4
Homo sapiens Protein: SREBF2
Summary
InnateDB Protein IDBP-378428.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SREBF2
Protein Name sterol regulatory element binding transcription factor 2
Synonyms bHLHd2; SREBP-2; SREBP2;
Species Homo sapiens
Ensembl Protein ENSP00000395728
InnateDB Gene IDBG-9448 (SREBF2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 81 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 81 [view]
Protein-Protein 73 [view]
Protein-DNA 7 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 1 [view]
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0046983 protein dimerization activity
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
PFAM PF00010
PRINTS
PIRSF
SMART SM00353
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3V0I8
UniProt Splice Variant
Entrez Gene 6721
UniGene Hs.443258
RefSeq
HUGO HGNC:11290
OMIM 600481
CCDS
HPRD 02726
IMGT
EMBL AL021453 CH471095 Z99716
GenPept EAW60470

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca