InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IGFBP1

Summary

InnateDB Protein

IDBP-374643.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IGFBP1

Protein Name

insulin-like growth factor binding protein 1

Synonyms

AFBP; hIGFBP-1; IBP1; IGF-BP25; PP12;

Species

Homo sapiens

Ensembl Protein

ENSP00000413511

InnateDB Gene

IDBG-15764 (IGFBP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	2 [view]
Protein-DNA	11 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005520	insulin-like growth factor binding

Biological Process

GO:0001558

regulation of cell growth

Cellular Component

GO:0005576

extracellular region

Protein Structure and Domains

PDB ID

InterPro

IPR000716 Thyroglobulin type-1
IPR000867 Insulin-like growth factor-binding protein, IGFBP
IPR009030 Insulin-like growth factor binding protein, N-terminal
IPR022321 Insulin-like growth factor-binding protein family 1-6, chordata
IPR022322 Insulin-like growth factor-binding protein 1

PFAM

PF00086
PF00219

PRINTS

PR01976
PR01977

PIRSF

SMART

SM00211
SM00121

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt