Homo sapiens Protein: THRB
Summary
InnateDB Protein IDBP-367992.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol THRB
Protein Name thyroid hormone receptor, beta
Synonyms C-ERBA-2; C-ERBA-BETA; ERBA2; GRTH; NR1A2; PRTH; THR1; THRB1; THRB2;
Species Homo sapiens
Ensembl Protein ENSP00000414100
InnateDB Gene IDBG-22332 (THRB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 72 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 72 [view]
Protein-Protein 71 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0004887 thyroid hormone receptor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0030522 intracellular receptor signaling pathway
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001628 Zinc finger, nuclear hormone receptor-type
IPR001728 Thyroid hormone receptor
PFAM PF00105
PRINTS PR00047
PR00546
PIRSF
SMART SM00399
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JNQ4
UniProt Splice Variant
Entrez Gene 7068
UniGene Hs.741539
RefSeq
HUGO HGNC:11799
OMIM 190160
CCDS
HPRD 07521
IMGT
EMBL AC012087 AC093927 AC098971 AC099054 AC112217
GenPept