InnateDB Protein
|
IDBP-366001.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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BCR
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Protein Name
|
breakpoint cluster region
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Synonyms
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ALL; BCR1; CML; D22S11; D22S662; PHL;
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Species
|
Homo sapiens
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Ensembl Protein
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ENSP00000396531
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InnateDB Gene
|
IDBG-2349 (BCR)
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Protein Structure
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|
Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 93 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated |
Total |
93
[view]
|
Protein-Protein |
92
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
1
[view]
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
8 [view]
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0005089
|
Rho guanyl-nucleotide exchange factor activity
|
|
Biological Process |
GO:0032321
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positive regulation of Rho GTPase activity
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GO:0035023
|
regulation of Rho protein signal transduction
|
GO:0035556
|
intracellular signal transduction
|
|
Cellular Component |
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PDB ID |
|
InterPro |
IPR000219
Dbl homology (DH) domain
|
PFAM |
PF00621
|
PRINTS |
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PIRSF |
|
SMART |
SM00325
|
TIGRFAMs |
|
Modification |
|
SwissProt |
|
PhosphoSite |
PhosphoSite-
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TrEMBL |
H0Y554
|
UniProt Splice Variant |
|
Entrez Gene |
613
|
UniGene |
Hs.715409
|
RefSeq |
|
HUGO |
HGNC:1014
|
OMIM |
151410
|
CCDS |
|
HPRD |
01044
|
IMGT |
|
EMBL |
U07000
|
GenPept |
|
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