InnateDB Protein
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IDBP-292688.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TBC1D14
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Protein Name
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TBC1 domain family, member 14
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000386921
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InnateDB Gene
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IDBG-9167 (TBC1D14)
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Protein Structure
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Function |
Negative regulator of starvation-induced autophagosome formation. {ECO:0000269PubMed:22613832}.
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Subcellular Localization |
Golgi apparatus, cis-Golgi network {ECO:0000269PubMed:22613832}. Golgi apparatus, trans-Golgi network {ECO:0000269PubMed:22613832}. Note=After amino acid starvation, Golgi apparatus-associated protein levels increase compared with fed conditions. May be cycling between the Golgi apparatus and an endosomal pool, redistributing to the Golgi apparatus upon starvation.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
9
[view]
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Protein-Protein |
9
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000195
Rab-GTPase-TBC domain
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PFAM |
PF00566
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PRINTS |
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PIRSF |
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SMART |
SM00164
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TIGRFAMs |
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Modification |
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SwissProt |
Q9P2M4
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PhosphoSite |
PhosphoSite-Q9P2M4
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TrEMBL |
C9JP26
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UniProt Splice Variant |
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Entrez Gene |
57533
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UniGene |
Hs.518611
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RefSeq |
NP_065824
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HUGO |
HGNC:29246
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OMIM |
614855
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CCDS |
CCDS3394
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HPRD |
11623
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IMGT |
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EMBL |
AB037743
AB449900
AC092463
AC097382
AC106045
AL833868
BC041167
CH471131
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GenPept |
AAH41167
BAA92560
BAH16643
CAD38726
EAW82375
EAW82376
EAW82377
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