InnateDB Protein
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IDBP-292495.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CDC45
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Protein Name
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cell division cycle 45 homolog (S. cerevisiae)
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Synonyms
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CDC45L; CDC45L2; PORC-PI-1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000384978
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InnateDB Gene
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IDBG-1383 (CDC45)
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Protein Structure
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|
Function |
Required for initiation of chromosomal DNA replication.
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Subcellular Localization |
Cytoplasm. Nucleus.
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Disease Associations |
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Tissue Specificity |
Widely expressed, highest levels are found in adult testis and thymus and in fetal liver.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
41
[view]
|
Protein-Protein |
36
[view]
|
Protein-DNA |
4
[view]
|
Protein-RNA |
0
|
DNA-DNA |
1
[view]
|
RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
1 [view]
|
|
|
Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003874
CDC45 family
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PFAM |
PF02724
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PRINTS |
|
PIRSF |
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SMART |
|
TIGRFAMs |
|
Modification |
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SwissProt |
O75419
|
PhosphoSite |
PhosphoSite-O75419
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TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
8318
|
UniGene |
Hs.742418
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RefSeq |
NP_001171482
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HUGO |
HGNC:1739
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OMIM |
603465
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CCDS |
CCDS54500
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HPRD |
09145
|
IMGT |
|
EMBL |
AC000082
AC000087
AC000088
AF053074
AF062495
AF081535
AJ223728
AK293123
AK293338
AY358971
AY572790
BC006232
BC010022
BT006792
CH471176
CT841513
|
GenPept |
AAC27289
AAC67521
AAD08998
AAH06232
AAH10022
AAP35438
AAQ89330
AAS66985
BAG56675
BAG56854
CAA11530
CAJ86443
EAX03036
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