InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Trp53bp1

Summary

InnateDB Protein

IDBP-259802.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Trp53bp1

Protein Name

transformation related protein 53 binding protein 1

Synonyms

53BP1; m53BP1; p53BP1; Tp53bp1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000106278

InnateDB Gene

IDBG-201919 (Trp53bp1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 111 interaction(s) predicted by orthology.

Experimentally validated
Total	22 [view]
Protein-Protein	15 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	7 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	111 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001102	RNA polymerase II activating transcription factor binding
GO:0001104	RNA polymerase II transcription cofactor activity
GO:0002039	p53 binding
GO:0003684	damaged DNA binding
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0035064	methylated histone binding
GO:0042162	telomeric DNA binding

Biological Process

GO:0006281	DNA repair
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0006974	cellular response to DNA damage stimulus
GO:0045944	positive regulation of transcription from RNA polymerase II promoter