InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PLD4

Summary

InnateDB Protein

IDBP-245344.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PLD4

Protein Name

phospholipase D family, member 4

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000376372

InnateDB Gene

IDBG-22839 (PLD4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004435	phosphatidylinositol phospholipase C activity
GO:0004630	phospholipase D activity
GO:0005515	protein binding
GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity

Biological Process

GO:0002244	hematopoietic progenitor cell differentiation
GO:0006644	phospholipid metabolic process
GO:0006655	phosphatidylglycerol biosynthetic process
GO:0006909	phagocytosis
GO:0008152	metabolic process
GO:0016042	lipid catabolic process
GO:0043647	inositol phosphate metabolic process
GO:0044281	small molecule metabolic process
GO:0046474	glycerophospholipid biosynthetic process

Cellular Component

GO:0005634	nucleus
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane
GO:0032588	trans-Golgi network membrane
GO:0045335	phagocytic vesicle