Homo sapiens Protein: EFCAB6
Summary
InnateDB Protein IDBP-237907.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EFCAB6
Protein Name EF-hand calcium binding domain 6
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000379533
InnateDB Gene IDBG-10675 (EFCAB6)
Protein Structure
UniProt Annotation
Function Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex. {ECO:0000269PubMed:12612053}.
Subcellular Localization Nucleus {ECO:0000269PubMed:12612053}.
Disease Associations
Tissue Specificity Specifically expressed in the testis. {ECO:0000269PubMed:12612053}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
IPR015070 EF-hand calcium-binding domain-containing protein 6
PFAM PF00036
PF13202
PF13405
PF08976
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5THR3
PhosphoSite PhosphoSite-Q5THR3
TrEMBL
UniProt Splice Variant
Entrez Gene 64800
UniGene Hs.658996
RefSeq NP_942153
HUGO HGNC:24204
OMIM
CCDS CCDS14050
HPRD 13391
IMGT
EMBL AB051459 AB073862 AK027241 AK292411 AK292498 AL023801 AL031843 AL118498 AL355841 BC039315 Z82201 Z97055
GenPept AAH39315 BAB15703 BAB33342 BAB71780 BAF85100 BAF85187 CAB91065 CAQ07046 CAQ07047 CAQ09926 CAQ09928 CAQ10020 CAQ10022 CAQ10334 CAQ11050