Homo sapiens Protein: FGFRL1 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||
InnateDB Protein | IDBP-232958.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | FGFRL1 | ||||||||||||
Protein Name | fibroblast growth factor receptor-like 1 | ||||||||||||
Synonyms | |||||||||||||
Species | Homo sapiens | ||||||||||||
Ensembl Protein | ENSP00000381498 | ||||||||||||
InnateDB Gene | IDBG-6367 (FGFRL1) | ||||||||||||
Protein Structure | |||||||||||||
UniProt Annotation | |||||||||||||
Function | Has a negative effect on cell proliferation. {ECO:0000250}. | ||||||||||||
Subcellular Localization | Membrane {ECO:0000269PubMed:12813049}; Single-pass type I membrane protein {ECO:0000269PubMed:12813049}. Note=Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles. | ||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen. {ECO:0000269PubMed:11031111, ECO:0000269PubMed:11267671, ECO:0000269PubMed:11418238}. | ||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|
||||||||||||
Gene Ontology | |||||||||||||
Molecular Function |
|
||||||||||||
Biological Process |
|
||||||||||||
Cellular Component |
|
||||||||||||
Protein Structure and Domains | |||||||||||||
PDB ID | |||||||||||||
InterPro |
IPR003598
Immunoglobulin subtype 2 IPR003599 Immunoglobulin subtype IPR007110 Immunoglobulin-like domain IPR013098 Immunoglobulin I-set IPR013106 Immunoglobulin V-set domain IPR013151 Immunoglobulin |
||||||||||||
PFAM |
PF07679
PF07686 PF00047 |
||||||||||||
PRINTS | |||||||||||||
PIRSF | |||||||||||||
SMART |
SM00408
SM00409 |
||||||||||||
TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | Q8N441 | ||||||||||||
PhosphoSite | PhosphoSite-Q8N441 | ||||||||||||
TrEMBL | D6REM7 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 53834 | ||||||||||||
UniGene | Hs.628675 | ||||||||||||
RefSeq | |||||||||||||
HUGO | HGNC:3693 | ||||||||||||
OMIM | 605830 | ||||||||||||
CCDS | CCDS3344 | ||||||||||||
HPRD | 16163 | ||||||||||||
IMGT | |||||||||||||
EMBL | AC019103 AF279689 AF312678 AJ277437 AK314365 AY358303 BC015228 BC036769 | ||||||||||||
GenPept | AAH15228 AAH36769 AAK15273 AAK26742 AAQ88670 BAG36996 CAC14171 | ||||||||||||