InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gsx1

Summary

InnateDB Protein

IDBP-208991.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gsx1

Protein Name

GS homeobox 1

Synonyms

Gsh-1; Gsh1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000069728

InnateDB Gene

IDBG-208989 (Gsx1)

Protein Structure

UniProt Annotation

Function

Probable transcription factor that binds to the DNA sequence 5'-GC[TA][AC]ATTA[GA]-3'. Activates the transcription of the GHRH gene. Plays an important role in pituitary development. {ECO:0000269PubMed:8631293}.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0021527	spinal cord association neuron differentiation
GO:0021854	hypothalamus development
GO:0021984	adenohypophysis development
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048663	neuron fate commitment