InnateDB Protein
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IDBP-169989.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ppap2c
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Protein Name
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phosphatidic acid phosphatase type 2C
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Synonyms
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Lpp2;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000069670
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InnateDB Gene
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IDBG-169987 (Ppap2c)
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Protein Structure
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Function |
Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1- phosphate (S-1-P) (By similarity). {ECO:0000250}.
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Subcellular Localization |
Membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
Expressed at high levels in lung, liver and kidney; at low levels in heart and brain, and was not detected in skeletal muscle.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
5 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1354945
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InterPro |
IPR000326
Phosphatidic acid phosphatase type 2/haloperoxidase
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PFAM |
PF01569
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PRINTS |
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PIRSF |
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SMART |
SM00014
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TIGRFAMs |
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Modification |
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SwissProt |
Q9DAX2
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PhosphoSite |
PhosphoSite-Q9DAX2
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TrEMBL |
G3XA61
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UniProt Splice Variant |
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Entrez Gene |
50784
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UniGene |
Mm.28873
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RefSeq |
NP_056632
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MGI ID |
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MGI Symbol |
Ppap2c
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OMIM |
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CCDS |
CCDS35966
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HPRD |
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IMGT |
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EMBL |
AC100708
AF123611
AK005452
AK049581
BC010332
CH466553
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GenPept |
AAD24061
AAH10332
BAB24045
BAC33824
EDL31694
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