Mus musculus Protein: Grap2
Summary
InnateDB Protein IDBP-163811.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Grap2
Protein Name GRB2-related adaptor protein 2
Synonyms Gads; GRAP-2; GRB2L; GRBLG; GrbX; Grf40; GRID; GrpL; Mona; P38;
Species Mus musculus
Ensembl Protein ENSMUSP00000046532
InnateDB Gene IDBG-163809 (Grap2)
Protein Structure
UniProt Annotation
Function Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Endosome {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Experimentally validated
Total 43 [view]
Protein-Protein 43 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005768 endosome
Protein Structure and Domains
PDB ID MGI:1333842
InterPro IPR000980 SH2 domain
IPR001452 SH3 domain
IPR011511 Variant SH3 domain
PFAM PF00017
PF14633
PF00018
PF14604
PF07653
PRINTS PR00401
PR00452
PIRSF
SMART SM00252
SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O89100
PhosphoSite PhosphoSite-O89100
TrEMBL Q3U0E8
UniProt Splice Variant
Entrez Gene 17444
UniGene
RefSeq NP_034945
MGI ID 2W10
MGI Symbol Grap2
OMIM
CCDS CCDS27663
HPRD
IMGT
EMBL AF053405 AF055465 AF129477 AF236118 AJ011735 AK156939 BC052496 CH466550
GenPept AAC98669 AAD08803 AAD41783 AAF60318 AAH52496 BAE33906 CAA09756 EDL04599