InnateDB Protein
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IDBP-154113.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Slc10a1
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Protein Name
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solute carrier family 10 (sodium/bile acid cotransporter family), member 1
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Synonyms
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Ntcp;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000093229
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InnateDB Gene
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IDBG-154111 (Slc10a1)
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Protein Structure
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Function |
The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.
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Subcellular Localization |
Membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
Accession |
GO Term |
GO:0008508
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bile acid:sodium symporter activity
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GO:0015125
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bile acid transmembrane transporter activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:97379
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InterPro |
IPR002657
Bile acid:sodium symporter
IPR004710
Bile acid transporter
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PFAM |
PF01758
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O08705
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PhosphoSite |
PhosphoSite-O08705
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
20493
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UniGene |
Mm.486361
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RefSeq |
NP_035517
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MGI ID |
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MGI Symbol |
Slc10a1
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OMIM |
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CCDS |
CCDS49101
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HPRD |
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IMGT |
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EMBL |
AB003303
BC021154
BC094023
U95131
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GenPept |
AAB81023
AAH21154
AAH94023
BAA19846
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